KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED13L
All Species:
22.73
Human Site:
S2058
Identified Species:
41.67
UniProt:
Q71F56
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q71F56
NP_056150.1
2210
242602
S2058
P
N
S
S
P
V
P
S
P
G
S
P
S
G
I
Chimpanzee
Pan troglodytes
XP_001138050
2188
240763
S2036
L
P
A
S
P
T
G
S
P
V
H
S
P
G
S
Rhesus Macaque
Macaca mulatta
XP_001112106
2210
242628
S2058
P
N
S
S
P
V
P
S
P
G
S
P
S
G
I
Dog
Lupus familis
XP_534693
2280
250152
S2128
P
N
S
S
P
V
P
S
P
G
S
P
S
G
I
Cat
Felis silvestris
Mouse
Mus musculus
Q6JPI3
2207
241740
S2055
P
N
S
S
P
V
P
S
P
G
S
P
S
G
I
Rat
Rattus norvegicus
NP_001101807
1374
149708
G1224
S
S
P
V
P
S
P
G
S
P
S
G
I
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509907
2170
238695
S2018
L
P
A
S
P
T
G
S
P
V
H
S
P
G
S
Chicken
Gallus gallus
XP_415317
2195
241321
S2043
P
N
S
S
P
V
P
S
P
G
S
P
S
G
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A2VCZ5
2102
230974
N1948
D
L
I
N
I
I
P
N
S
P
T
T
S
P
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KTX8
2618
280005
N2460
T
H
M
D
R
V
S
N
H
G
S
P
G
R
M
Honey Bee
Apis mellifera
XP_393643
1982
216109
G1832
D
G
G
G
S
G
L
G
N
H
D
G
P
G
S
Nematode Worm
Caenorhab. elegans
Q93442
2862
325119
S2709
D
L
G
L
E
T
P
S
S
A
A
I
R
Q
T
Sea Urchin
Strong. purpuratus
XP_001203054
1127
123639
G977
E
P
I
P
T
D
G
G
P
A
P
A
A
Q
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
53.7
99.2
93.3
N.A.
92.4
57.7
N.A.
53.5
86.4
N.A.
50.2
N.A.
24.8
33.9
21.2
25.6
Protein Similarity:
100
69.3
99.6
94.7
N.A.
95.7
59.9
N.A.
69.7
92.5
N.A.
66.4
N.A.
41.5
50.5
38.5
35.1
P-Site Identity:
100
33.3
100
100
N.A.
100
26.6
N.A.
33.3
100
N.A.
13.3
N.A.
26.6
6.6
13.3
6.6
P-Site Similarity:
100
40
100
100
N.A.
100
40
N.A.
40
100
N.A.
46.6
N.A.
46.6
6.6
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
0
0
0
0
0
16
8
8
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
24
0
0
8
0
8
0
0
0
0
8
0
0
0
0
% D
% Glu:
8
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
16
8
0
8
24
24
0
47
0
16
8
70
8
% G
% His:
0
8
0
0
0
0
0
0
8
8
16
0
0
0
0
% H
% Ile:
0
0
16
0
8
8
0
0
0
0
0
8
8
0
39
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
16
16
0
8
0
0
8
0
0
0
0
0
0
0
0
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
0
39
0
8
0
0
0
16
8
0
0
0
0
0
0
% N
% Pro:
39
24
8
8
62
0
62
0
62
16
8
47
24
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
8
8
0
% R
% Ser:
8
8
39
54
8
8
8
62
24
0
54
16
47
0
24
% S
% Thr:
8
0
0
0
8
24
0
0
0
0
8
8
0
0
8
% T
% Val:
0
0
0
8
0
47
0
0
0
16
0
0
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _